Skip to main content

PREPARE: UNC Center for Bioethics Researchers Work Overseas

March 29, 2023

Members of the PRomoting Equity for Pregnant Adolescents in Research (PREPARE) team recently returned from a trip to Botswana and Malawi. This study is led by Principal Investigators (PI) Anne Lyerly, MD, MA, and Kristen Sullivan, PhD, MSW, MBA, of the UNC Center for Bioethics, and includes several UNC Bioethics faculty. While overseas, the PREPARE … Read more

Beyond the Medical: The ELSI of Polygenic Scores for Social Traits

August 12, 2022

UNC Center for Bioethics core faculty member Jean Cadigan, Ph.D., along with a multidisciplinary team of researchers from across the country, was recently awarded an R01 grant from the National Human Genome Research Institute at NIH entitled, Beyond the Medical: The ELSI of Polygenic Scores for Social Traits.

PREPARE (PRomoting Equity for Pregnant Adolescents in REsearch)

October 22, 2021

Annie Lyerly and Kristen Sullivan have been awarded an R01 from the National Institute of Allergy and Infectious Disease (NIAID) to develop empirically informed guidance for conducting ethically responsible HIV/co-infections research with pregnant adolescents.  Pregnant adolescents face synergistic challenges in the context of HIV – heightened risk of maternal infection, vertical transmission, and maternal and … Read more

Study to Examine Physicians’ Pandemic Stress (STEPPS)

October 14, 2021

Mara Buchbinder has launched the Study to Examine Physicians’ Pandemic Stress (STEPPS) with funding from the Greenwall Foundation and the National Institute for Occupational Safety and Health. The COVID-19 pandemic has intensified ongoing stress, overwork, and disillusionment among the healthcare workforce. Healthcare professionals responding to the pandemic are experiencing crises of moral integrity and personal … Read more

New Collaboration between UNC and Stellenbosch University, South Africa

September 16, 2021

The Research for Ethical Data Science in Southern Africa (REDSSA) project has the overall aims of producing new knowledge regarding the ethical, legal and social implications (ELSI) of conducting data science research to develop evidence-based, context specific guidance for the conduct and governance of data science initiatives such as DS-I Africa, and to strengthen the … Read more

Ethical Dimensions of Peanut Allergy Immunotherapy Research

August 19, 2021

With funding from the National Institute of Allergy & Infectious Diseases (NIAID), Dr. Jill Fisher is conducting a research study on pediatric clinical trials for food allergies, focusing primarily on peanut allergy. Using ethnographic research methods, the project investigates the on-the-ground ethical challenges that emerge in these clinical trials. In particular, the project explores how … Read more

Incidental Enhancements: A Neglected Governance Challenge for Human Genome Editing Research

June 25, 2020

The increasing pace and international diffusion of developments in human genome editing research have prompted ongoing efforts to develop responsible governance for such research. One point of broad agreement across these efforts is that human genome editing research should prioritize medical applications over attempts to enhance human traits because of the moral concerns the latter … Read more

Healthy Volunteers as Model Organisms

September 5, 2017

Comparative Research Ethics and Policy for Phase I Trials Principal Investigators: Jill A. Fisher and Rebecca L. Walker This project addresses the need for a novel evidence-based approach to the protection of Phase I healthy volunteers. Phase I clinical trials test the safety of investigational drugs that eventually may be used in affected patients. These trials … Read more

Ethics of HIV-Related Research Involving Adolescents in Kenya

August 7, 2017

Despite the high social value of adolescent HIV prevention research in sub-Saharan Africa, investigators are reluctant to involve adolescents in studies with HIV testing and disclosure of results because of ethical concerns about the risks of their participation. This study examines four inter-related ethical issues essential to adolescent HIV research: the effects of disclosure of … Read more

Acute Infection: Lived Experiences and Ethical Challenges in HIV Research

February 6, 2017

A better understanding of acute HIV infection is essential to public health, impacting both HIV transmission and potential advances in HIV cure clinical research. Acute HIV infection refers to the earliest stages of HIV infection, the short window of time right after a person becomes infected when they are most infectious. Individuals diagnosed and treated … Read more