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Beyond the Medical: The ELSI of Polygenic Scores for Social Traits

August 12, 2022

UNC Center for Bioethics core faculty member Jean Cadigan, Ph.D., along with a multidisciplinary team of researchers from across the country, was recently awarded an R01 grant from the National Human Genome Research Institute at NIH entitled, Beyond the Medical: The ELSI of Polygenic Scores for Social Traits.

Hospital Policies During COVID-19: An Analysis of Visitor Restrictions

January 23, 2022

Abstract Objective: In response to the COVID-19 pandemic, hospitals have developed visitor restriction policies in order to mitigate spread of infection. We reviewed hospital visitor restriction policies for consistency and to develop recommendations to highlight fair and transparent restrictions, exceptions, and appeals in policy development and implementation. Design: Collection and analysis of public-facing visitor restriction … Continued

Translational Science: A Survey of US Biomedical Researchers’ Perspectives and Practices

December 23, 2021

This national survey aimed to identify how biomedical researchers using vertebrate animals viewed issues of significance for translational science, including oversight and public engagement, and to analyze how researcher characteristics and animal model choice correlate with those views. Responses from 1,187 researchers showed awareness of, and concerns about, problems of translation, reproducibility and rigor. Surveyed … Continued

The View from the Benches: Scientists’ Perspectives on the Uses and Governance of Human Gene-Editing Research

August 26, 2021

The advent of human gene editing has stimulated international interest in how best to govern this research. However, research on stakeholder views has neglected scientists themselves. We surveyed 212 scientists who use gene editing in their work. Questions captured views on oversight and use of somatic and germline human gene editing for treatment, prevention, and … Continued

Biomedical Researchers’ Perceptions of the NIH’s Sex as a Biological Variable Policy for Animal Research: Results from a U.S. National Survey

August 26, 2021

Background: In 2015, the National Institutes of Health (NIH) established a policy on sex as a biological variable (SABV) in an effort to address the overrepresentation of men and male animals in biomedical research and the lack of attention to sex-based responses to medical treatments. However, questions remain regarding how U.S. biomedical researchers perceive the … Continued