Inclusive Pedagogy, Department of Philosophy, UNC CH, April 28 2022

This national survey aimed to identify how biomedical researchers using vertebrate animals viewed issues of significance for translational science, including oversight and public engagement, and to analyze how researcher characteristics and animal model choice correlate with those views. Responses from 1,187 researchers showed awareness of, and concerns about, problems of translation, reproducibility and rigor. Surveyed … Read more

The Hastings Center recently announced the election of 24 new fellows, which include Jill A. Fisher, PhD and Rebecca L. Walker, PhD in the UNC Department of Social Medicine. The Hastings Center is pleased to announce the election of 24 new fellows. Hastings Center fellows are a group of more than 200 individuals of outstanding … Read more

This chapter considers the ethical significance of the translational value of biomedical research using live nonhuman animals. By “translational value” is meant how well or poorly animal research results in specific improvements in human medicine. While other animal as well as environmental benefits may also result from biomedical research using animals, the primary objective of … Read more

Background/aims Financial compensation for research participation is a major focus of ethical concern regarding human subject recruitment. Phase I trials are sometimes considered to be a lucrative source of income for healthy volunteers, encouraging some people to become “professional guinea pigs.” Yet, little is known about how much these clinical trials actually pay and how … Read more

Background: In 2015, the National Institutes of Health (NIH) established a policy on sex as a biological variable (SABV) in an effort to address the overrepresentation of men and male animals in biomedical research and the lack of attention to sex-based responses to medical treatments. However, questions remain regarding how U.S. biomedical researchers perceive the … Read more

For years, genomic medicine—medicine based on the growing understanding of the genetic contribution to many diseases and conditions—has been hailed as the future of medical treatment, but it has thus far had limited effect on day-to-day medical practice. The ultimate goal of genomic medicine has always been the ability not just to identify dangerous gene … Read more

Background: Since the National Institutes of Health (NIH) Revitalization Act of 1993, focus on the equitable inclusion of women in clinical research has been ongoing. NIH’s 2015 sex as a biological variable (SABV) policy aims to transform research design, analysis, and reporting in the preclinical sphere by including male and female organisms in vertebrate animal … Read more

Abstract This book review essay discusses Principles of Animal Research Ethics (2020), by Tom L. Beauchamp and David DeGrazia. Review Animal research has long been a focus of social controversy and ethical debate. As Tom Beauchamp and David DeGrazia summarize in Principles of Animal Research Ethics, use of animal subjects incapable of consent, in ways … Read more