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Inclusive Pedagogy

April 28, 2022

Inclusive Pedagogy, Department of Philosophy, UNC CH, April 28 2022

Translational Science: A Survey of US Biomedical Researchers’ Perspectives and Practices

December 23, 2021

This national survey aimed to identify how biomedical researchers using vertebrate animals viewed issues of significance for translational science, including oversight and public engagement, and to analyze how researcher characteristics and animal model choice correlate with those views. Responses from 1,187 researchers showed awareness of, and concerns about, problems of translation, reproducibility and rigor. Surveyed … Continued

Fisher, Walker Elected as Hastings Center Fellows

December 2, 2021

The Hastings Center recently announced the election of 24 new fellows, which include Jill A. Fisher, PhD and Rebecca L. Walker, PhD in the UNC Department of Social Medicine. The Hastings Center is pleased to announce the election of 24 new fellows. Hastings Center fellows are a group of more than 200 individuals of outstanding … Continued

Biomedical Research Using Nonhuman Animals: Ethics and Translational Value

August 30, 2021

This chapter considers the ethical significance of the translational value of biomedical research using live nonhuman animals. By “translational value” is meant how well or poorly animal research results in specific improvements in human medicine. While other animal as well as environmental benefits may also result from biomedical research using animals, the primary objective of … Continued

Phase I Trial Compensation: How Much Do Healthy Volunteers Actually Earn from Clinical Trial Enrollment?

August 26, 2021

Background/aims Financial compensation for research participation is a major focus of ethical concern regarding human subject recruitment. Phase I trials are sometimes considered to be a lucrative source of income for healthy volunteers, encouraging some people to become “professional guinea pigs.” Yet, little is known about how much these clinical trials actually pay and how … Continued

Biomedical Researchers’ Perceptions of the NIH’s Sex as a Biological Variable Policy for Animal Research: Results from a U.S. National Survey

August 26, 2021

Background: In 2015, the National Institutes of Health (NIH) established a policy on sex as a biological variable (SABV) in an effort to address the overrepresentation of men and male animals in biomedical research and the lack of attention to sex-based responses to medical treatments. However, questions remain regarding how U.S. biomedical researchers perceive the … Continued

A New Governance Overnance Approach to Regulating Human Genome Editing

December 10, 2020

For years, genomic medicine—medicine based on the growing understanding of the genetic contribution to many diseases and conditions—has been hailed as the future of medical treatment, but it has thus far had limited effect on day-to-day medical practice. The ultimate goal of genomic medicine has always been the ability not just to identify dangerous gene … Continued

Evaluating the National Institutes of Health’s Sex as a Biological Variable Policy: Conflicting Accounts from the Front Lines of Animal Research

December 1, 2020

Background: Since the National Institutes of Health (NIH) Revitalization Act of 1993, focus on the equitable inclusion of women in clinical research has been ongoing. NIH’s 2015 sex as a biological variable (SABV) policy aims to transform research design, analysis, and reporting in the preclinical sphere by including male and female organisms in vertebrate animal … Continued

Can We Do without Respect and Justice in Animal Research Ethics?

October 23, 2020

Abstract This book review essay discusses Principles of Animal Research Ethics (2020), by Tom L. Beauchamp and David DeGrazia. Review Animal research has long been a focus of social controversy and ethical debate. As Tom Beauchamp and David DeGrazia summarize in Principles of Animal Research Ethics, use of animal subjects incapable of consent, in ways … Continued