The conduct of clinical research often involves two distinguishable sets of relationships: the researcher-subject relationship, and the clinician-patient relationship. Some scholars argue that being a patient in a clinical care setting and a subject in a research study are so different that anything that would promote in subjects the view that they are in clinician-patient … Read more

Ambitions and efforts to control human aging are presently flourishing within biomedicine, but under the banners of two competing professional camps. On one side is an “anti-aging” movement of entrepreneurs and clinicians, offering dietary supplements, cosmetics, hormone injections, and other goods and services to combat aging and its effects. On the other side are biogerontologists—biologists … Read more

In their Policy Forum “HIV testing in China”, Z. Wu et al. describe the new Chinese national program of active, provider-initiated HIV/AIDS testing among prisoners and other high-risk groups. For some groups, such as prisoners and government workers, individuals consent to health examinations that include an HIV test, rather than directly consenting to the test … Read more

This paper provides a simultaneously reflexive and analytical framework to think about obstacles to truly informed consent in social science and biomedical research. To do so, it argues that informed consent often goes awry due to procedural misconceptions built into the research context. The concept of procedural misconception is introduced to describe how individuals respond … Read more

Change in the way new drugs are developed, including the privatisation of clinical trials, has altered the arrangement and roles of healthcare professions. In this paper I examine one aspect of this change: the role of research coordinators in the conduct of contract research in the United States. My focus on coordinators highlights the ethical … Read more

Gene transfer often has multiple and unpredictable effects on cells. The high hope of genetic medicine for 30 years has been to develop a way of using recombinant DNA techniques to treat patients through the genes involved in their diseases. As Richard Roblin, scientific director of the Council on Bioethics of the President of the … Read more

The critique of vulnerability offered by Levine et al. (2004) affirms recent discussions about the disutility of this imputed characteristic of individuals and groups for protecting research subjects. Being “too broad,” vulnerability stereotypes whole categories of individuals, and everyone might be considered vulnerable. Being “too narrow,” vulnerability’s focus on group characteristics diverts attention from features … Read more

The growth of public and professional interest in “anti-aging” interventions raises an ethical problem for the medical profession with important policy implications: is human aging an appropriate target for medical intervention? At present there is nothing that medicine can prescribe to combat aging that has any scientific validation (Olshansky, Hayflick, Carnes, 2002). But biogerontologists are … Read more

Some people dispute the relative importance of issues in genetics and biotechnology for the future of bioethics, either because they think the problems are time-limited or because they give priority to issue of human rights and social justice in health care. In fact, the special historical standing of genetic issue s in bioethics reflects four … Read more

Lisa Morgan arrives in the office of Dr. Karen Anderson, her obstetrician/gynecologist. Dr. Anderson, who is going over her schedule for the day, hopes that Lisa is not pregnant again. Less than 2 years ago, Dr. Anderson had performed a therapeutic abortion for Lisa, who is now 20 years old and unmarried. The doctor’s concerns … Read more